A camera of all-weather vehicle driver monitoring system is designed to detect the driver′s abnormal driving behavior and improve driving safety. The RGB-IR CMOS image sensor, dual band-pass filter lens, hardware circuit, and active infrared lighting technology of the camera are studied in this work. Firstly, infrared enhancement characteristics of the RGB-IR CMOS image sensor are analyzed. Secondly, parameters of the lens are chosen to design according to the application scene and the suitable CMOS image sensor. The optical structure of the lens is optimized and a dual band-pass filter is also selected. Thirdly, the overall design of the camera hardware circuit is completed. Finally, the imaging performance of the camera and the effectiveness of the algorithm are evaluated. The experimental results show that the camera can achieve daytime high-definition color imaging and high-definition infrared imaging at night. The camera can meet the standards of the vehicle specification level and the image can be transmitted over a long distance of 10~ 15 m. In addition, the camera also has the advantages of low cost and high stability.