Aiming at the problem that the underground gas pipeline leakage positioning accuracy is not high, according to the characteristic of infrasound waves generated with leakage points when gas pipeline leaks, an infrasound source location algorithm of gas pipeline leakage is proposed. The algorithm builds positioning model, and the position of the leak point is obtained by the geometric relationship between the sensor nodes and the leak point. Firstly, the infrasound wave signals generated by the gas pipeline leaks are collected through a sensor array, and the signals are processed by wavelet denoising. Then the time delay between adjacent sensor nodes is calculated by the generalized crosscorrelation method, and finally the location of the leak point is calculated by combining the geometric model of the leak location. The signal preprocessing part of the algorithm is simulated, and the simulation experiment of leak location is carried out in the laboratory. The results show that the positioning error of the algorithm is within 1 m in the gas pipeline leakage location, and it has high positioning accuracy.