| 孙长龙,季 忠,钟文韬.基于近红外光谱的脑血氧无创监测系统研究[J].电子测量与仪器学报,2022,36(4):136-144 |
| 基于近红外光谱的脑血氧无创监测系统研究 |
| Research on non-invasive monitoring system based on cerebralblood oxygen on near infrared spectroscopy |
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| DOI： |
| 中文关键词: 脑血氧 近红外 四波长 LED Valsalva 运动 |
| 英文关键词:cerebral blood oxygen near infrared four-wavelength LED Valsalva exercise |
| 基金项目:国家自然科学基金（81971700）、重庆市研究生科研创新项目（CYS20075）、重庆市自然科学基金项目（2020CDJ LHZZ 032）资助 |
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| 中文摘要: |
| 目前临床使用的脑血氧无创监测设备大多为双波长,由于黑色素的吸收会导致测量结果出现偏差,因此需要对测量结
果进行修正。 为此本文基于近红外光谱无创监测脑血氧的基本原理,针对现有脑血氧无创监测设备的不足,考虑前额叶的光学
特性,研制了一种四波长探测光源(700、760、805、850 nm)以及双路光电检测器的脑血氧无创监测传感装置,并建立了光谱吸光
度的数学模型,在此基础上构建了新型的脑血氧无创监测系统,实现了可抑制皮肤黑色素成分干扰的脑血氧信息无创测量。 最
后通过对 Valsalva 运动以及空载的对照实验进行秩和分析,初步验证了本系统的有效性。 |
| 英文摘要: |
| At present, most of the non-invasive monitoring equipment for cerebral blood oxygen in clinical use is dual-wavelength.
Because the absorption of melanin will cause deviations in the measurement results, the measurement results need to be corrected. For
this reason, based on the basic principle of non-invasive monitoring of cerebral blood oxygen by near infrared spectroscopy, in view of the
shortcomings of existing non-invasive monitoring equipment for cerebral blood oxygen, considering the optical characteristics of the
prefrontal lobe, a four-wavelength detection light source (700, 760, 805, 850 nm) and a dual-channel photoelectric detector for noninvasive monitoring of cerebral blood oxygen, and a mathematical model of spectral absorbance is established. On this basis, a new type
of non-invasive monitoring system for cerebral blood oxygen is constructed, which can inhibit the interference of skin melanin components
to non-invasively measure the cerebral blood oxygen information. Finally, through the rank sum analysis of the Valsalva exercise and noload control experiments, the effectiveness of the system is preliminarily verified. |
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